Journal: Biology of Reproduction
Article Title: IL11 Antagonist Inhibits Uterine Stromal Differentiation, Causing Pregnancy Failure in Mice 1
doi: 10.1095/biolreprod.108.073601
Figure Lengend Snippet: PEGIL11A diminished IL11-induced pSTAT3 in human endometrial epithelial cells (HES) in vitro. A) Immunoblot for pSTAT3 and total STAT3 in cell lysates from HES cells. B) Graphical representation of pSTAT3/total STAT3 ratios calculated from densitometry (mean ± SEM; * indicates significant difference from other treatments; n = 5 for all treatments except PEG where n = 2).
Article Snippet: We are grateful to Melinda Marwood, Joanne Yap, Jun Gu, and Dr. Neil Borg (Prince Henry's Institute) for their excellent technical assistance; Drs. Felicity Dunlop, Pierre Scotney, Manuel Baca, and Andrew Nash (CSL Limited) for providing the IL11 antagonists and technical assistance; Dr. D.A.
Techniques: In Vitro, Western Blot